The 1954 Salk poliomyelitis vaccine field trial.

Experimental study of interference between Pertussis antigens and Salk Poliomyelitis vaccine

TIIE BIGGEST PUBLIC IIEALTH EXPERIMENT EVER: The 1954 Field Trial of the Salk Poliomyelitis Vaccine

THE LARGEST and most expensive medical experiment in history was carried out in 1954. Well over a million young children participated, and the immediate direct costs were over 5 million dollars. The experiment was carried out to assess the effectiveness, if any, of the Salk vaccine as a protection against paralysis or death from poliomyelitis. The study was elaborate in many respects, most prom...

Poliomyelitis Vaccine

The Epidemiology of poliomgelitis has been investigated in our country Pasteur Institute; the incidence of Poliomgelitis, after the age of 4 years i's rare, in Iran.  Passive antibody of maternal origin do not interfere with production of active antibody after immunization.  Inactivated Polio Vaccine (salk) has been effective in reducing the incidence of poliomge­litis by approximately 90 per ...

The Case for Live Poliovirus Vaccination **

Large scale programs for the control of poliomyelitis through the use of active immunization can be said to have started, both in the United States and elsewhere, in 1955. This step marked the end of a 40-year period in which experimental efforts to vaccinate against poliomyelitis had been repeatedly tried. As early as 1910, Dr. Simon Flexner, the Director of the Rockefeller Institute, and at t...

A New Dimension in Documentation through Association of Ideas

1. D. Bodian, Am. J. Hyg. 55, 414 (1952). 2. D. M. Horstmann, Proc. Soc. Exptl. BRiol. Med. 79, 417 (1952). 3. , R. W. McCollum, A. D. Mascola, J. Exptl. Med. 99, 355 (1954). 4. D. Bedian and R. S. Paffenbarger, Jr., Amiz. J. Hyg. 60, 83 (1954). 5. D. Bodian, Ibid. 57, 81 (1953). 6. This work was aided by a grant from the National Foundation for Infantile Paralysis. 7. J. F. Enders, T. H. Welle...